Related Experiment Video
Updated: Jun 19, 2026
Ultrasonographic Evaluation of Breast Cancer-related Lymphedema
Published on: January 12, 2017
Breast self-examination: defining a cohort still in need
Lee G Wilke1, Gloria Broadwater, Sarah Rabiner
1Duke University, Department of Surgery, Durham, NC, USA. wilke031@mc.duke.edu
Background:
The value of breast self-examination (BSE) to detect early breast cancer is controversial.
Methods:
Within an institutional review board-approved prospective study, 147 high-risk women were enrolled from 2004 to 2007. Yearly clinical examination, BSE teaching, and mammography were performed simultaneously followed by interval breast magnetic resonance imaging (MRI). Women underwent additional BSE teaching at 6 months. Women reporting a mass on BSE underwent clinical evaluation.
Results:
Fourteen breast cancers were detected in 12 women. BSE detected 6/14 breast cancers versus 6/14 detected by MRI and 2/14 by mammography. Of 24 masses detected by BSE, 6/24 were malignant. The sensitivity, specificity, and predictive value of BSE to detect breast cancer were 58.3%, 87.4%, and 29.2%, respectively. The sensitivity, specificity, and predictive value of a Breast Image Reporting and Data System (BI-RADS) score of >or=4 on MRI were 66.7%, 88.9%, and 34.8%, respectively.
Conclusions:
BSE detects new breast cancers in high-risk women undergoing screening mammogram, CBE, and yearly breast MRI.
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