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Severe secretory diarrhea with elevated gastrin-releasing peptide controlled by somatostatin analogue: a case report
R Alhindawi1, M Deitel, J Kempston
1Department of Surgery, University of Toronto, Ont.
Abstract:
Gastrin-releasing peptide immunoreactivity has been seen in functioning endocrine tumours which are recognized as a major cause of secretory diarrhea. The authors describe a case of a 52-year-old woman who had secretory diarrhea (5 L/d) with markedly elevated gastrin-releasing peptide levels associated with islet cell hyperplasia. No tumour could be identified. The diarrhea was controlled by somatostatin analogue.