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Updated: Jun 19, 2026
08:36
Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction
Published on: November 1, 2018
Control of dengue virus translation and replication
Suman M Paranjape1, Eva Harris
1Science and Technology Policy Fellowship Program, American Association for the Advancement of Sciences, 1200 New York Avenue NW, Washington, DC 20005, USA. sumip1@gmail.com
Current Topics in Microbiology and Immunology
|October 6, 2009
Summary
Dengue virus replication and translation are increasingly understood through new research on RNA elements and host factors. This knowledge aids in developing antiviral strategies and understanding viral infections.
Area of Science:
- Virology
- Molecular Biology
- Public Health
Background:
- Dengue poses a growing global public health risk.
- Decades of research have advanced understanding of dengue virus replication and translation.
- Emerging methodologies reveal insights into RNA elements, viral, and host factors influencing dengue virus.
Purpose of the Study:
- To review current research on cellular and molecular mechanisms of dengue virus infection.
- To explore future research directions in dengue virus replication and translation.
- To discuss the role of host cell factors in viral processes and antiviral strategy development.
Main Methods:
- Literature review and integration of research findings.
- Analysis of studies on RNA elements, viral factors, and host factors.
- Exploration of cellular and molecular mechanisms of dengue virus.
Main Results:
- Significant progress has been made in understanding dengue virus translation and replication mechanisms.
- New methodologies have enhanced the comprehension of modulating factors.
- The role of host cell factors is crucial for viral replication and translation.
Conclusions:
- Integrating research findings provides a comprehensive view of dengue virus infection mechanisms.
- Understanding dengue virus molecular processes informs strategies for other viral infections.
- Knowledge of dengue virus replication, translation, and host interactions facilitates the development of novel antiviral therapies.
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