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Contraceptive choices: is the future with men?

Ra Anderson¹, Mj Walton

¹Centre for Reproductive Biology, University of Edinburgh, Edinburgh, UK.

Women'S Health (London, England)

|October 7, 2009

Summary

Developing a reversible male contraceptive is a priority. Hormonal contraception is closest to market, with Phase III trials in China and commercial studies in Europe, offering a potential rival to female methods.

Area of Science:

Reproductive medicine
Contraceptive development
Men's health

Background:

A highly effective, reversible male contraceptive is needed to match female options.
Current research explores multiple targets for male contraception.
Significant progress has been made in hormonal male contraception.

Purpose of the Study:

To review the challenges and timeline for male contraceptive development.
To highlight the most promising current approaches.
To assess the potential launch of new male contraceptive methods.

Main Methods:

Review of various male contraceptive targets including spermatogenesis, testicular proteins, immunocontraception, and vas deferens.
Focus on hormonal contraception as the leading candidate.

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Analysis of ongoing clinical trials (Phase III in China, commercial studies in Europe).

Main Results:

Hormonal contraception is the most advanced method currently.
Phase III clinical trials in China are nearing completion.
Commercial studies are actively progressing in Europe.

Conclusions:

Hormonal male contraception is the closest to market availability.
Further development and regulatory approvals are anticipated.
A launch is becoming increasingly likely in the near future.