Uterine artery embolization and future fertility potential

Area of Science:

• Gynecology
• Interventional Radiology
• Reproductive Medicine

Background:

• Uterine artery embolization (UAE) is increasingly used for symptomatic fibroids.
• It offers advantages for specific patient groups, including those with anesthesia risks or transfusion objections.
• Current evidence on UAE's impact on fertility and pregnancy is limited.

Purpose of the Study:

• To review the available literature on the safety and efficacy of UAE for women desiring conception.
• To identify gaps in knowledge regarding UAE's effects on ovarian function, uterine function, and pregnancy outcomes.
• To provide guidance for women considering UAE and future pregnancy.

Main Methods:

• Literature review of case reports and series.
• Analysis of existing data on UAE safety and efficacy.
• Assessment of concerns regarding ovarian and uterine function post-UAE.

Main Results:

• Case reports suggest positive outcomes for fertility, but significant concerns remain.
• Limited data exists on long-term effects on ovarian reserve and uterine function.
• Subsequent pregnancy outcomes and potential risks to offspring are not well-established.

Conclusions:

• UAE's effects on fertility and subsequent pregnancy are uncertain.
• Long-term data and randomized controlled trials are necessary.
• Conception after UAE is currently inadvisable due to potential risks to fertility and pregnancy outcomes.