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Updated: Jun 19, 2026

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
Published on: August 8, 2022
Genetics and coronary heart disease
1INSERM , U525, CHU Pitié-Salpétrière, Université Paris VI, 91 bd de l'Hôpital 75013, Paris, France. cambien@chups.jussieu.fr
Abstract:
Genetic analysis is absolutely required to understand the architecture of complex diseases such as coronary heart disease, and such knowledge may lead to important advances in the diagnosis and treatment of the disease. On the other hand, there is presently little theoretical and empirical evidence supporting the idea that large-scale diagnostic and prognostic genetic testing for coronary heart disease might be medically useful. The situation may change however, as recent technological and population genomics advances are progressively incorporated in new appropriately designed studies.
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