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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Is multislice computed tomography of value for the imaging of myocardial infarction?

Karam Souibri1, Gerald M Pohost

  • 1Division of Cardiovascular Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Future Cardiology
|October 7, 2009
PubMed

Insights

Cardiovascular magnetic resonance (CMR) imaging and multislice computed tomography (MSCT) both accurately assess acute myocardial infarction. However, MSCT involves radiation and contrast risks, and cannot detect myocardial scarring, unlike CMR.

Area of Science:

  • Cardiology
  • Radiology
  • Medical Imaging

Background:

  • Myocardial contrast-enhanced (CE) cardiovascular magnetic resonance (CMR) imaging is a validated technique for assessing myocardial infarction.
  • Multislice computed tomography (MSCT) is a newer imaging modality suggested for acute myocardial infarction.
  • Both techniques offer high resolution and are less invasive than catheterization.

Purpose of the Study:

  • To evaluate the effectiveness of 16-slice computed tomography (MSCT) in assessing myocardial viability in acute myocardial infarction.
  • To compare MSCT with cardiovascular magnetic resonance (CMR) imaging for infarct assessment.
  • To determine the most appropriate imaging approach for acute and chronic myocardial infarction.

Main Methods:

  • Comparison of myocardial viability assessment between MSCT and CE-CMR.
  • Evaluation of infarct localization and size determination using both imaging modalities.
  • Assessment of limitations including radiation exposure, contrast agent risks, and scar imaging capabilities.

Main Results:

  • Both MSCT and CMR demonstrated agreement in infarct localization and size determination.
  • MSCT exposes patients to significant ionizing radiation.
  • MSCT requires iodinated contrast agents, posing potential kidney risks.
  • MSCT cannot visualize myocardial scarring, a key consequence of infarction.

Conclusions:

  • While both MSCT and CMR can identify acute myocardial infarction, CMR offers advantages in assessing myocardial scarring.
  • MSCT's risks (radiation, contrast) must be weighed against its benefits.
  • The choice of imaging modality should consider the need to evaluate both acute damage and chronic scarring.

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