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Related Experiment Video

Updated: Jun 19, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

Can vascular closure devices reduce complications?

Timothy A Sanborn¹

¹Northwestern University, Feinberg School of Medicine, Division of Cardiology, Evanston Northwestern Healthcare, 2650 Ridge Avenue, Evanston, IL 60201, USA. tsanborn@enh.org

Future Cardiology

|October 7, 2009

Summary

Vascular closure devices offer faster healing and improved comfort for patients. Modern devices may even reduce vascular complications compared to manual compression, particularly after percutaneous coronary interventions.

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Area of Science:

Cardiovascular Medicine
Interventional Cardiology
Medical Device Technology

Background:

Vascular closure devices (VCDs) were initially developed to expedite hemostasis and ambulation post-procedure.
Early concerns existed regarding potential increased complication rates with first-generation VCDs.
Advancements in VCD technology have prompted re-evaluation of their safety and efficacy profile.

Purpose of the Study:

To assess the evolving role and safety of vascular closure devices in clinical practice.
To compare complication rates between VCDs and manual compression, especially in specific patient populations.
To evaluate the impact of device improvements on patient outcomes and procedural efficiency.

Main Methods:

Review of industry-sponsored, randomized clinical trials on vascular closure devices.
Analysis of complication data from early-generation versus modern VCDs.
Comparative assessment against manual compression techniques, focusing on percutaneous coronary interventions.

Main Results:

Initial trials showed VCDs reduced hemostasis and ambulation times, enhancing patient comfort.
Concerns about higher complication rates with early devices have largely diminished.
Current trends suggest modern VCDs may offer reduced vascular complications compared to manual compression.

Conclusions:

Vascular closure devices are effective in improving patient recovery times and comfort.
The safety profile of VCDs has improved, addressing earlier concerns.
Modern VCDs show a potential advantage over manual compression in reducing vascular complications, particularly for percutaneous coronary interventions.