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SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients

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Drug-induced confusional states: the usual suspects?

A Hufschmidt¹, V Shabarin, T Zimmer

¹Department of Neurology, Verbundkrankenhaus Bernkastel-Wittlich, Koblenzer Str. 91, D-54516, Wittlich, Germany. a.hufschmidt@t-online.de

Acta Neurologica Scandinavica

|October 7, 2009

Summary

Diuretics, dopaminergic drugs, and antidepressants are common causes of acute confusional state (ACS) in hospitalized patients. This condition is often linked to undiagnosed dementia.

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Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

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Published on: January 13, 2018

Area of Science:

Geriatric Medicine
Clinical Pharmacology
Neurology

Background:

Acute confusional state (ACS) is a common reason for hospital admissions.
Identifying causative agents is crucial for effective management.

Purpose of the Study:

To retrospectively analyze the frequency of individual drugs implicated in drug-induced ACS.
To identify the most common drug classes responsible for ACS.

Main Methods:

Retrospective analysis of hospital admissions for acute confusion.
Identification and categorization of causative drugs.

Main Results:

Drug-induced ACS accounted for 18.8% of 346 admissions.
Dopaminergic drugs (24.2%), diuretics (15.1%), and antidepressants (13.6%) were most frequent.
Nearly half of patients had dementia, often undiagnosed.

Conclusions:

Diuretics, via hyponatremia, are a significant cause of ACS.
Drug-induced ACS is a considerable issue, particularly in patients with dementia.