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A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
Electrocardiographic findings, device therapies, and comorbidities in octogenarian implantable defibrillator
James D Daniels1, Justin Saunders, Sunthosh Parvathaneni
1The North Texas VA Health Sciences Center, Dallas, Texas, USA. James.Daniels@UTSouthwestern.edu
Insights
Octogenarians receiving implantable cardioverter-defibrillators (ICDs) show similar arrhythmia episodes and health outcomes compared to younger patients. Age alone should not prevent octogenarians from receiving ICDs, though ECG findings like sinus bradycardia and LBBB are more common.
Area of Science:
- Cardiology
- Geriatric Medicine
- Medical Devices
Background:
- Implantable cardioverter-defibrillators (ICDs) are crucial for preventing sudden cardiac death.
- The safety and efficacy of ICDs in octogenarians (patients aged 80 and older) remain incompletely understood.
Purpose of the Study:
- To evaluate baseline electrocardiographic (ECG) findings in octogenarians undergoing ICD implantation.
- To compare arrhythmia episodes, device therapies, and non-arrhythmic morbidity/mortality between octogenarians and younger patient cohorts.
Main Methods:
- Retrospective review of 199 patients aged 70+ who received ICDs.
- Patients categorized into three age groups: 70-74, 75-79, and 80+ years.
- Analysis of baseline ECGs, device interrogations, and clinical outcomes.
Main Results:
- Octogenarians exhibited higher rates of sinus bradycardia and left bundle branch block.
- No significant differences were observed in the incidence of atrial fibrillation or AV block among age groups.
- Rates of any ICD therapy, appropriate/inappropriate shocks, and time to first therapy were similar across all age groups.
- Development of severe non-arrhythmic illness or death did not differ significantly between octogenarians and younger patients.
Conclusions:
- Octogenarians receiving ICDs experience comparable arrhythmic events and clinical outcomes to younger individuals.
- Higher prevalence of sinus bradycardia and LBBB in octogenarians may impact pacing strategies.
- Age alone should not be a contraindication for ICD implantation in very elderly patients.
Background:
The use of implantable cardioverter-defibrillators (ICDs) in octogenarians is poorly defined.
Objective:
To assess baseline electrocardiographic (ECG) findings, arrhythmia episodes, and development of severe nonarrhythmic illness or death in patients aged >or=80 years at ICD implantation, and to compare them with younger patients.
Methods:
Medical records and device interrogations for 199 patients >or=70 years old who underwent ICD implantation were reviewed. Patients were divided into 3 groups based on age at the time of implant: age 70-74 (group 1; 88 patients), age 75-79 (group 2; 67 patients), and age >or=80 (group 3; 44 patients).
Results:
ECGs: Octogenarians were more likely to have sinus bradycardia (SB) (P = 0.047) and left bundle branch block (LBBB) (P = 0.043) compared to younger patients. There was no difference among groups in the proportion of patients with atrial fibrillation or any degree of AV block. THERAPIES: There was no difference between age groups in any therapy (P = 0.78), appropriate therapy (P = 0.54), or inappropriate therapy (P = 0.21) per patient-year. There was no difference between groups in time-to-first therapy of any type (P = 0.71). NONARRHYTHMIC DEATH/MORBIDITY: There was no difference between groups in time to death or serious illness.
Conclusion:
Our study is the first to evaluate in detail the therapies received by octogenarians after ICD placement. The higher incidence of SB and LBBB might influence the number of pacing sites in octogenarian patients. Very elderly patients have similar rates of arrhythmic episodes and development of severe comorbidities as septuagenarians, and they should not be denied ICD implantation based solely on age.
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