A 10-year retrospective study on palladium sensitivity
Olayemi Durosaro1, Rokea A el-Azhary
1Department of Dermatology and Mayo Medical School, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Background:
Palladium has become an important contact allergen because of increased use in industry, jewelry, and dentistry.
Objective:
To determine the frequency of palladium allergy in a US patch-test population tested to palladium.
Methods:
A 10-year retrospective review (1997-2006) was performed on patients sensitive to palladium at the Department of Dermatology, Mayo Clinic, Rochester, MN.
Results:
A total of 910 patients were tested to a series that included palladium chloride 2% in petrolatum. A palladium-positive patch-test result was noted in 110 patients (12.1%). Of the 106 patients sensitized to palladium who had records available for review, 15.1% had a diagnosis of lichen planus-like eruptions; 13.2%, burning mouth; 27.4%, stomatitis; and 29.2%, hand and body dermatitis.
Conclusion:
Palladium sensitivity is more common in oral diseases than in skin. We describe a previously unknown high degree of co-reactivity of gold with palladium to the same degree as the known co-reactivity with nickel.
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