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Updated: Jun 19, 2026

SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy
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SNARE-mediated Fusion of Single Proteoliposomes with Tethered Supported Bilayers in a Microfluidic Flow Cell Monitored by Polarized TIRF Microscopy

Published on: August 24, 2016

CAPS drives trans-SNARE complex formation and membrane fusion through syntaxin interactions

Declan J James1, Judith Kowalchyk, Neil Daily

  • 1Department of Biochemistry, University of Wisconsin, Madison, WI 53706, USA.

Proceedings of the National Academy of Sciences of the United States of America
|October 7, 2009
PubMed
Summary

Ca(2+)-dependent activator protein for secretion (CAPS) accelerates vesicle fusion by promoting SNARE complex formation. This priming protein organizes SNAREs on the plasma membrane, impacting regulated exocytosis.

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