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Updated: Jun 19, 2026

Precise, High-throughput Analysis of Bacterial Growth
Published on: September 19, 2017
Metabolism, cell growth and the bacterial cell cycle
1Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA. jdwang@bcm.edu
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Adaptation to fluctuations in nutrient availability is a fact of life for single-celled organisms in the 'wild'. A decade ago our understanding of how bacteria adjust cell cycle parameters to accommodate changes in nutrient availability stemmed almost entirely from elegant physiological studies completed in the 1960s. In this Opinion article we summarize recent groundbreaking work in this area and discuss potential mechanisms by which nutrient availability and metabolic status are coordinated with cell growth, chromosome replication and cell division.
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