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Published on: June 5, 2019
Marital status and heart rate variability in patients with suspected coronary artery disease
Gemma Randall1, Mimi R Bhattacharyya, Andrew Steptoe
1Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London, UK. g.randall@ucl.ac.uk
Insights
Being unmarried is linked to poorer heart rate variability (HRV), a key indicator of cardiovascular health. This finding may explain why married individuals experience lower rates of heart disease.
Area of Science:
- Cardiology
- Psychophysiology
- Social Determinants of Health
Background:
- Marriage is associated with reduced cardiovascular disease (CVD) risk.
- Impaired heart rate variability (HRV) is linked to CVD and social isolation.
- Understanding the interplay between social factors and cardiovascular health is crucial.
Purpose of the Study:
- To investigate the association between heart rate variability (HRV) and marital status.
- To examine HRV in patients with suspected coronary artery disease (CAD).
Main Methods:
- Eighty-eight patients undergoing investigation for suspected CAD were recruited.
- 24-hour electrocardiograms were used to measure heart rate variability.
- Frequency and time-domain analyses were applied to HRV data.
Main Results:
- Unmarried status was significantly associated with reduced HRV.
- This association remained independent of age, gender, medication, and depression.
- Reduced HRV was observed across both frequency and time-domain measures.
Conclusions:
- Lower heart rate variability is linked to not being married.
- This HRV difference may mediate the protective effect of marriage on cardiovascular health.
- Marital status is an important factor influencing cardiovascular outcomes.
Background:
Married individuals are at reduced risk of cardiovascular disease morbidity and mortality. Recent research indicates that impaired heart rate variability (HRV) may contribute to cardiovascular disease morbidity and mortality and has also been associated with social isolation.
Purpose:
We investigated associations between HRV and marital status in patients with suspected coronary artery disease (CAD).
Methods:
Eighty-eight patients who were being investigated for suspected CAD (28 women, 60 men, mean age 61.6, 60% married) were recruited from three rapid access chest pain clinics in London. Heart rate variability was measured using 24-h electrocardiograms and analyzed using frequency and time-domain measures.
Results:
Unmarried marital status was associated with reduced heart rate variability as indexed by both frequency and time-domain measures, independently of age, gender, beta-blocker use, depression ratings, and subsequent diagnosis of significant CAD.
Conclusion:
These findings suggest that reduced heart rate variability is associated with not being married and may contribute to the reliably observed relationship between marital status and cardiovascular disease morbidity and mortality.
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