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Updated: Jun 19, 2026

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Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Advanced laser techniques for filler-induced complications
Daniel Cassuto1, Ovidio Marangoni, Giorgio De Santis
1Department of Plastic Surgery, University of Catania, Catania, Italy. daniel.cassuto@fastwebnet.it
Summary
Laser treatments effectively resolve disfiguring facial nodules caused by injectable fillers. This minimally invasive approach offers a successful alternative to surgery for patients experiencing long-term complications from dermal fillers.
Area of Science:
- Dermatology
- Medical Aesthetics
- Laser Surgery
Background:
- Increasing use of injectable fillers leads to disfiguring complications like anaerobic infections and granulomas.
- Facial nodules resulting from various gel fillers present a significant cosmetic and medical challenge.
Purpose of the Study:
- To present two laser-assisted evacuation techniques for treating disfiguring facial nodules caused by injectable fillers.
- To evaluate the efficacy and safety of laser treatments for filler-induced complications.
Main Methods:
- Lithium triborate laser (532 nm) used for draining infectious hydrogel lesions and removing infected material.
- 808-nm diode laser employed for intralesional treatment of granulomas from microparticle-containing gels, melting and liquefying components for evacuation.
- Both laser systems featured controllable thin beams to minimize tissue damage, pain, and discomfort.
Main Results:
- Successful reduction or complete resolution of disfiguring nodules observed in all 20 treated patients.
- Increased resolution rates were noted with repeated laser treatment sessions.
- The procedures were well-tolerated, with minimal discomfort and pain.
Conclusions:
- Laser-assisted evacuation provides a successful and minimally invasive treatment option for long-standing disfiguring nodules from injectable fillers.
- This approach expands therapeutic options for adverse reactions to fillers, offering lower morbidity and less cosmetic disfigurement compared to surgical removal.