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Updated: Jun 19, 2026
10:22
Humanized Mediator Release Assay as a Read-Out for Allergen Potency
Published on: June 29, 2021
Compilation of international standards for patch testing methodology and allergens.
Lily S Cheng1, Ali Alikhan, Howard I Maibach
1School of Medicine, University of California at Davis, Sacramento, CA, USA.
Dermatitis : Contact, Atopic, Occupational, Drug
|October 8, 2009
Summary
Patch testing recommendations for contact dermatitis vary globally. This study compiles current guidelines, highlighting differences and the need for international collaboration in allergen testing.
Area of Science:
- Dermatology
- Allergology
- Clinical Immunology
Background:
- Global variations exist in patch testing methodology and allergen recommendations for contact dermatitis.
- A comprehensive compilation of these international guidelines is currently lacking.
Purpose of the Study:
- To systematically summarize existing recommendations for patch testing methodology.
- To compile a list of commonly recommended allergens used in patch testing worldwide.
Main Methods:
- Conducted a literature search to identify relevant patch testing guidelines.
- Contacted representatives from 24 international contact dermatitis groups to gather data.
Main Results:
- Thirteen contact dermatitis groups provided responses regarding their recommendations.
- Significant variations in recommended allergens and testing methodologies were observed.
- Most groups align their recommendations with the European baseline series for patch testing.
Conclusions:
- Observed differences in patch testing protocols emphasize the necessity for enhanced international collaboration.
- Further harmonization of guidelines can improve diagnostic accuracy and patient care in contact dermatitis.
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