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Related Experiment Video

Updated: Jun 19, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Does prematurity affect platelet indices?

A Wasiluk¹, J Osada, M Dabrowska

¹Department of Neonatology, Medical University of Bialystok, Bialystok, Poland. awasiluk@umwb.edu.pl

Advances in Medical Sciences

|October 8, 2009

Summary

Preterm newborns have lower platelet counts and hematocrit, with higher platelet distribution width compared to full-term infants. These platelet indices may aid in diagnosing hemostatic disorders in neonates.

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A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

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Published on: January 7, 2018

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Last Updated: Jun 19, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

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Published on: November 20, 2015

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

Published on: January 7, 2018

Area of Science:

Neonatal Medicine
Hematology
Pediatrics

Background:

Platelet indices are crucial for assessing hemostasis.
Understanding neonatal platelet characteristics is vital for clinical management.

Purpose of the Study:

To compare key blood platelet indices between preterm newborns (PTN) and full-term newborns (FTN).

Main Methods:

Blood samples were collected from the umbilical artery of 51 PTN and 55 FTN.
Platelet count, platelet hematocrit (PCT), mean platelet volume (MPV), and platelet distribution width (PDW) were analyzed.

Main Results:

PTN exhibited significantly lower platelet counts (197 x 10^3/µL) versus FTN (287 x 10^3/µL).
Platelet hematocrit (PCT) was lower in PTN (0.16%) compared to FTN (0.22%).
Platelet distribution width (PDW) was elevated in PTN (50.64%) relative to FTN (46.54%).

Conclusions:

Reduced platelet count, PCT, and increased PDW in PTN may indicate effects of low gestational age or placental dysfunction.
Blood platelet indices are potentially vital for diagnosing neonatal hemostatic disorders.