Related Experiment Video
Updated: Jun 19, 2026

Application of High-speed Super-resolution SPEED Microscopy in Live Primary Cilium
Published on: January 16, 2018
Compact integration factor methods in high spatial dimensions
Qing Nie1, Frederic Y M Wan, Yong-Tao Zhang
1Department of Mathematics, University of California, Irvine, CA 92697-3875, United States.
Abstract:
The dominant cost for integration factor (IF) or exponential time differencing (ETD) methods is the repeated vector-matrix multiplications involving exponentials of discretization matrices of differential operators. Although the discretization matrices usually are sparse, their exponentials are not, unless the discretization matrices are diagonal. For example, a two-dimensional system of N × N spatial points, the exponential matrix is of a size of N(2) × N(2) based on direct representations. The vector-matrix multiplication is of O(N(4)), and the storage of such matrix is usually prohibitive even for a moderate size N. In this paper, we introduce a compact representation of the discretized differential operators for the IF and ETD methods in both two- and three-dimensions. In this approach, the storage and CPU cost are significantly reduced for both IF and ETD methods such that the use of this type of methods becomes possible and attractive for two- or three-dimensional systems. For the case of two-dimensional systems, the required storage and CPU cost are reduced to O(N(2)) and O(N(3)), respectively. The improvement on three-dimensional systems is even more significant. We analyze and apply this technique to a class of semi-implicit integration factor method recently developed for stiff reaction-diffusion equations. Direct simulations on test equations along with applications to a morphogen system in two-dimensions and an intra-cellular signaling system in three-dimensions demonstrate an excellent efficiency of the new approach.
Related Concept Videos
Triple Integrals over General Regions
Triple Integrals in Rectangular Coordinates
Changing the Order of Integration in Triple Integrals
Substitutions in Multiple Integrals
Iterated Integrals and Fubini's Theorem
Real-Life Applications of Multiple Integrals

