Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrating Mathematical Modeling and Oncology: An Improvised Collocation Approach for Prediction of Chemotherapy Response.

Bulletin of mathematical biology·2026
Same author

Race and Vision Outcomes in Ranibizumab-Treated Participants With Diabetic Macular Edema: A Meta-Analysis.

JAMA ophthalmology·2025
Same author

Discourse on measurement.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Reply: "Integrity" Assessment Following Rhegmatogenous Retinal Detachment Repair.

Ophthalmic surgery, lasers & imaging retina·2025
Same author

Scleral fixated intraocular lens techniques for the vitreoretinal surgeon: an update.

Current opinion in ophthalmology·2024
Same author

Retinal Displacement Following Rhegmatogenous Retinal Detachment Repair.

Ophthalmic surgery, lasers & imaging retina·2024
Same journal

Hoarseness as a Manifestation of Chronic Lymphocytic Leukaemia Involving the Larynx.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Suggested Updates in Vascular Surgery Training in Pakistan.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Acute Pancreatitis Induced by Rhinovirus Infection.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Severe <em>Pneumocystis Jirovecii </em>Pneumonia in a Non-HIV Infant: The Diagnostic Value of Metagenomic Next-<br /> Generation Sequencing.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Comment on: Comparing Michigan Neuropathy Screening Instrument Scores with Plantar Sensory Nerve Conduction Studies in Diabetic Neuropathy.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Indigenous Hyperangulated Videolaryngoscope: Bridging a Critical Gap in Airway Management in Pakistan.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
See all related articles

Related Experiment Video

Updated: Jun 19, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Brain abscess in children.

Khubaib Shahzad1, M Haroon Hamid, M Ali Khan

  • 1Department of Paediatric Medicine, The Children's Hospital and the Institute of Child Health, Lahore.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|October 9, 2009
PubMed
Summary
This summary is machine-generated.

This study on pediatric brain abscesses found fever, vomiting, and headache as common symptoms. Early recognition of clinical signs and predisposing factors is crucial for effective management in children.

More Related Videos

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
10:38

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Published on: September 9, 2015

Related Experiment Videos

Last Updated: Jun 19, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
10:38

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos

Published on: September 9, 2015

Area of Science:

  • Pediatric Neurology
  • Infectious Diseases
  • Neuroimaging

Background:

  • Brain abscesses in children are serious infections requiring prompt diagnosis and treatment.
  • Understanding the clinical presentation, radiological findings, and common causative agents is vital for improving outcomes.

Purpose of the Study:

  • To investigate the clinical presentation, radiological characteristics, predisposing conditions, and causative organisms of brain abscess in pediatric patients.
  • To inform clinical practice and improve the management of pediatric brain abscesses.

Main Methods:

  • A descriptive study was conducted over two years (September 2001 to August 2003) at The Children's Hospital and the Institute of Child Health, Lahore.
  • Included were all children under 16 years presenting with brain abscess, analyzing demographic, clinical, and radiological data.
  • Attempts were made to identify predisposing conditions and isolate causative microorganisms.

Main Results:

  • Twenty-five pediatric cases of brain abscess were analyzed. Common symptoms included fever (72%), vomiting (48%), and headache (44%).
  • Predisposing conditions were identified in 68% of cases, with cyanotic congenital heart disease (32%) and otic infections (20%) being most frequent.
  • Causative organisms, including Staphylococcus aureus and various Gram-negative bacteria, were isolated in 40% of cases.

Conclusions:

  • Early recognition of clinical features and awareness of predisposing factors are essential for managing pediatric brain abscess.
  • Understanding the common microbial profile aids in guiding appropriate antimicrobial therapy.
  • Improved diagnostic and therapeutic strategies are needed for better patient outcomes.