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Related Concept Videos

Mate Choice01:20

Mate Choice

Mate choice—the decision about whom to mate with—is a type of natural selection, since animals must reproduce to pass down their genes. Mate choice is also called intersexual selection because the behavior occurs between the sexes.
The Y Chromosome Determines Maleness02:19

The Y Chromosome Determines Maleness

The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...
The Ratio of X Chromosome to Autosomes02:45

The Ratio of X Chromosome to Autosomes

In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
Dosage Compensation02:50

Dosage Compensation

In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with  distinct numbers of X chromosomes will have...
Testing a Claim about Population Proportion01:24

Testing a Claim about Population Proportion

A complete procedure for testing a claim about a population proportion is provided here.
There are two methods of testing a claim about a population proportion: (1) Using the sample proportion from the data where a binomial distribution is approximated to the normal distribution and (2) Using the binomial probabilities calculated from the data.
The first method uses normal distribution as an approximation to the binomial distribution. The requirements are as follows: sample size is large...
Development of the Sexual Organs in the Embryo and Fetus01:15

Development of the Sexual Organs in the Embryo and Fetus

Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...

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Effect of Male Accessory Gland Products on Egg Laying in Gastropod Molluscs
15:19

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Published on: June 22, 2014

Male pseudohermaphroditism.

Badar Murtaza1, Arshad Mehmood, Shahzad Saleem Shah

  • 1Department of General Surgery, Combined Military Hospital, Kharian. badar_murtaza@yahoo.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|October 9, 2009
PubMed
Summary
This summary is machine-generated.

A 40-year-old infertile male presented with cryptorchidism and was found to have a uterus, cervix, and fallopian tubes. This case highlights a rare intersex condition in an individual with a 46XY karyotype.

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Area of Science:

  • Reproductive Endocrinology
  • Human Genetics
  • Developmental Biology

Background:

  • Infertility in males can stem from various genetic and developmental factors.
  • Cryptorchidism, or undescended testes, is a common congenital anomaly that can impact fertility.
  • Disorders of sex development (DSD) encompass a range of conditions affecting chromosomal, gonadal, or anatomical sex.

Observation:

  • A 40-year-old infertile male with cryptorchidism and normal secondary sexual characteristics was evaluated.
  • Imaging studies (ultrasonography and CT) suggested a tumor in the right abdominal testis.
  • Surgical exploration revealed internal female reproductive organs (uterus, cervix, fallopian tubes) alongside abdominal testes.

Findings:

  • Histopathological examination confirmed the presence of both testicular and female reproductive tissues.
  • Karyotype analysis revealed a 46XY chromosomal complement.
  • The patient presented with a rare form of ovotesticular DSD with intra-abdominal gonads.

Implications:

  • This case underscores the importance of thorough investigation in cases of male infertility and cryptorchidism.
  • Understanding the spectrum of DSD is crucial for accurate diagnosis and management.
  • Such presentations challenge traditional binary classifications of sex and highlight the complexity of human sexual development.