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Dual resolution cone beam breast CT: a feasibility study.

Lingyun Chen¹, Youtao Shen, Chao-Jen Lai

¹Department of Imaging Physics, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4009, USA. lingyun.chen@di.mdacc.tmc.edu

Medical Physics

|October 9, 2009

Summary

This study shows a dual resolution breast CT technique can improve image quality and visibility of microcalcifications while reducing radiation dose. The breast-centered approach offers better dose savings than the VOI-centered approach.

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Area of Science:

Medical Imaging
Radiology
Cone Beam CT

Background:

Cone beam CT (CBCT) is a valuable tool in medical imaging.
Improving image quality and reducing radiation dose in breast imaging remains a critical challenge.

Purpose of the Study:

To assess the feasibility of a dual resolution volume-of-interest (VOI) cone beam breast CT technique.
To compare two implementation approaches (breast-centered vs. VOI-centered) for dose saving and scatter reduction.

Main Methods:

A dual resolution technique using a lead VOI mask and both CCD and flat panel (FP) detectors was developed.
Ray-tracing reprojection and Feldkamp-Davis-Kress filtered backprojection algorithms were employed for image reconstruction.
Monte Carlo simulations (GEANT4) evaluated dose saving and scatter reduction for both approaches.

Main Results:

The breast-centered approach demonstrated superior breast absorbed dose savings compared to the VOI-centered approach, with comparable scatter reduction.
Microcalcifications (MCs) invisible in standard FP CBCT scans became visible using the dual resolution FP-CCD CBCT technique in fatty breast phantoms.

Conclusions:

The dual resolution technique shows potential for enhancing image quality within the VOI.
This method offers the benefit of reduced radiation dose to the entire breast, both inside and outside the region of interest.