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Updated: Jun 19, 2026

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities

Published on: February 20, 2021

An effective correction algorithm for off-axis portal dosimetry errors.

Daniel W Bailey¹, Lalith Kumaraswamy, Matthew B Podgorsak

¹Department of Physics, State University of New York at Buffalo, Buffalo, New York 14260, USA.

Medical Physics

|October 9, 2009

Summary

This summary is machine-generated.

Accurate dose verification in intensity-modulated radiation therapy (IMRT) is improved by correcting for off-axis effects. This method enhances agreement between predicted and measured doses, especially near detector edges.

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Area of Science:

Medical Physics
Radiation Oncology
Radiotherapy Physics

Background:

Portal dosimetry is crucial for intensity-modulated radiation therapy (IMRT) pretreatment verification.
Significant dose errors (up to 15%) occur near detector edges due to off-axis effects.
Current methods struggle to accurately predict doses in these critical off-axis regions.

Purpose of the Study:

To develop and validate a method for correcting off-axis effects in portal dosimetry.
To improve the accuracy of dose verification for IMRT pretreatment.
To enhance the reliability of dose measurements near detector edges.

Main Methods:

Precisely correcting off-axis output factors used for imager calibration.
Implementing the correction method for portal dosimetric images.
Comparing predicted doses with measured doses before and after correction.

Main Results:

Agreement between predicted and measured doses improved by up to 15% for fields near detector edges.
Passing rates for gamma evaluation (3 mm, 3%) improved by as much as 60%.
The proposed method effectively accounts for off-axis effects, enhancing dose accuracy.

Conclusions:

Accurate calibration of off-axis output factors is essential for reliable portal dosimetry.
The developed method significantly improves IMRT pretreatment verification accuracy.
This approach enhances patient safety by ensuring precise dose delivery.