Related Experiment Videos
Atypical antipsychotics in the therapy of bipolar disorders: efficacy and safety
Rosaria Di Lorenzo1, Susanna Genedani
1Department of Mental Health, Presidio Psichiatrico di Diagnosi e Cura 1, Policlinico, via del Pozzo 71, I41100 Modena, Italy. saradiloren@interfree.itsaradiloren@interfree.it
Abstract:
Bipolar disorders are characterized by recurrent manic and depressive phases with early onset and poor prognosis for chronic symptoms and premature death. Almost a third of patients do not improve with the available treatments. Atypical antipsychotics have been tested in the treatment of bipolar disorder as an alternative to typical neuroleptics due to their safer side effect profile and have been hypothesized to be mood stabilizers on the basis of their activity on affective symptoms of schizophrenia. The most significant studies published up to now, concerning the use of clozapine, olanzapine, risperidone, quetiapine and ziprasidone in bipolar disorders are reviewed here. The receptor profile of these drugs is related to their side effects. Finally, the current indications of atypical antipsychotics and future research are discussed.
Related Concept Videos
Mania and Antimanic Drugs: Overview
Psychosis: Goals of Pharmacotherapy
Psychosis and Antipsychotic Drugs: Overview
Antipsychotic Drugs: Therapeutic Uses and Side Effects
Despite these side effects, antipsychotics are used therapeutically for various purposes, including managing schizophrenia, preventing nausea and vomiting, curbing...
Drug Therapy
Antianxiety Medications
Antipsychotic Drugs: Typical and Atypical Agents