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Updated: Jun 19, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Pharmacological treatment of pediatric obsessive-compulsive disorder
1Psychiatric Hospital for Children and Adolescents, University Hospital in Aarhus, Harald Selmers vej 66, 8240 Risskov, Denmark. pht@buh.aaa.dk
Abstract:
Obsessive-compulsive disorder is a far from rare neuropsychiatric disorder in children and adolescents which affects approximately 1-1.5% of the pediatric population. Obsessive-compulsive disorder is defined by the presence of obsessions and/or compulsions. It often takes a chronic course with either persistent, constantly distressing obsessive-compulsive symptoms or a waxing and waning course. The best documented and most efficient treatment is cognitive behavioural therapy and antidepressant medication with serotonin specific agents. In most cases, an improvement rate of 20-50% is reported following medication alone.
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