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Blood pressure and lipid control status in Japanese hypertensive patients
Yuko Ohta1, Takuya Tsuchihashi, Yuki Morinaga
1Division of Hypertension, Clinical Research Institute, National Kyushu Medical Center, Jigyohama 1-8-1, Chuo-ku, Fukuoka 810-8563, Japan. yukoo@kyumed.jp
Insights
Strict blood pressure (BP) and lipid control are crucial for preventing cardiovascular events. This study found that many hypertensive patients in Japan do not meet BP or LDL cholesterol goals, indicating a need for intensified treatment strategies.
Area of Science:
- Cardiology
- Hypertension Management
- Lipidology
Background:
- Cardiovascular events are significantly influenced by blood pressure (BP) and lipid levels.
- Effective management of hypertension and dyslipidemia is essential for patient outcomes.
Purpose of the Study:
- To assess the current status of BP and lipid control in hypertensive patients.
- To identify the proportion of patients achieving target BP and LDL cholesterol levels.
Main Methods:
- A cohort of 717 hypertensive patients at National Kyushu Medical Center was analyzed.
- BP goals were defined based on age (<65 years: <130/85 mmHg; ≥65 years: <140/90 mmHg).
- LDL cholesterol (LDL-C) goals were set according to Japanese guidelines based on patient risk categories.
Main Results:
- Average BP was 133/74 mmHg, and average LDL-C was 119 mg/dL.
- BP goals were met by 40% of younger and 67% of elderly patients.
- Overall, 65% of patients achieved their LDL-C goal, with 30% of those on lipid-lowering agents still not meeting targets.
- Only 39% of males and 36% of females achieved both BP and LDL-C goals.
Conclusions:
- A significant percentage of hypertensive patients, even those on medication, fail to achieve target BP and LDL-C levels.
- Current treatment strategies may be insufficient, necessitating more intensive interventions.
- Improved BP and lipid control in hypertensive patients is critical for reducing cardiovascular risk.
Abstract:
Strict blood pressure (BP) as well as lipid control is important to prevent cardiovascular events. The purpose of this study was to evaluate BP and lipid control status in hypertensive patients. Subjects were a total of 717 hypertensive patients who had been followed at National Kyushu Medical Center in FuKuoka, Japan. Goal BP was defined as < 130/85 mmHg (< 65 years) or < 140/90 mmHg (> or = 65 years). According to the Japanese guidelines, goal LDL cholesterol (LDL-C) levels were defined based on the patient category. Average BP level and the number of anti-hypertensive drugs were 133 + or - 12/74 + or - 9 mmHg and 2.1 + or - 1.1, respectively, and the LDL-C level was 119 + or - 27 mg/dl. Goal BP was achieved in 40% of the patients of < 65 years and 67% of the elderly patients. Goal LDL-C was achieved in 65% of the patients. Even in the patients taking lipid-lowering agents (n = 178), 30% failed to achieve goal LDL-C levels. In the patients who achieved BP < 130/85 mmHg, 67% also achieved goal LDL-C, whereas 61% of the patients whose BP > or = 140/90 mmHg achieved goal LDL-C. Both goal BP and LDL-C were achieved in 39% of the male and 36% of the female patients. In contrast, neither goal BP nor goal LDL-C was achieved in 16% of the male and 17% of the female patients. Results suggest that intensive intervention should be required to achieve satisfactory BP and lipid control in hypertensive patients.
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