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[Study of the APUD cells of the gastric mucosa]
G M Sampiero1, G Papalia, R Caruso
1Istituto di Chirurgia Generale, Università degli Studi di Messina.
Il Giornale Di Chirurgia
|October 1, 1990
Abstract:
The results of an histochemical and microscopic study of the APUD cells carried on gastric biopsies are reported. Endocrine cell hyperplasia, microscopically detected, was particularly evident in atrophic gastritis (type A chronic gastritis) and adenomas. The presence of the APUD cells confirmed by electronmicroscopy, which revealed granules of 200 NM with a central nucleus and a membrane-separating electron-lucent ring, gives a further contribution to the hypothesis of a possible association between endocrine cell hyperplasia and intestinal metaplasia.