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Updated: Jun 19, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Poststroke fatigue--a review.

Anners Lerdal¹, Linda N Bakken, Siren E Kouwenhoven

¹Department of Health Sciences, Buskerud University College, 3007 Drammen, Norway. anners.lerdal@hibu.no

Journal of Pain and Symptom Management

|October 9, 2009

Summary

Poststroke fatigue is a complex issue with multiple dimensions and contributing factors. Further research is needed to understand and manage this common condition effectively.

Related Experiment Videos

Last Updated: Jun 19, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Area of Science:

Neurology
Rehabilitation Medicine
Psychology

Background:

Fatigue is a prevalent complaint following stroke, significantly impacting patient recovery and quality of life.
Current understanding of poststroke fatigue's experience and contributing factors remains limited, hindering effective rehabilitation.
Developing patient-centered rehabilitation programs necessitates a comprehensive grasp of poststroke fatigue.

Purpose of the Study:

To synthesize existing literature on the description, definition, and measurement of poststroke fatigue.
To explore the relationship between poststroke fatigue and sociodemographic and clinical factors.
To identify potential antecedent components contributing to poststroke fatigue.

Main Methods:

Systematic literature search conducted in PubMed, CINAHL, EMBASE, and PsychInfo.
Keywords used: "stroke" OR "cerebrovascular accident" AND "fatigue".
Analysis of studies describing fatigue dimensions, definitions, measurement tools, and associated factors.

Main Results:

Poststroke fatigue is multidimensional; no specific theoretical definition exists, but a case definition is available.
General fatigue scales (e.g., Fatigue Severity Scale) are commonly used due to the absence of stroke-specific tools.
Sociodemographic factors (age, sex, living conditions, personality) and stroke characteristics show conflicting associations with fatigue.

Conclusions:

Prestroke fatigue appears related to poststroke fatigue, alongside personal factors, biomarkers, stroke characteristics, and comorbidity.
Conflicting findings highlight the complexity and need for further investigation into poststroke fatigue's etiology.
Continued empirical research with diverse theoretical perspectives is crucial to advance knowledge and improve patient care.