Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Industrialization and food safety for the Tsleil-Waututh Nation: An analysis of chemical levels in shellfish in Burrard Inlet.

Environmental research·2021
Same author

Effect of hydroxychloroquine on COVID-19 prevention in cancer patients undergoing treatment: study protocol for a randomized controlled trial.

Trials·2021
Same author

[Contribution of electronic cigarettes in smoking patients with psychotic disorders. A literature review].

L'Encephale·2021
Same author

Progressive delayed respiratory complications of sulfur mustard poisoning in 43 Iranian veterans, three decades after exposure.

Human & experimental toxicology·2018
Same author

Historical documentation of lead toxicity prior to the 20th century in English literature.

Human & experimental toxicology·2017
Same author

Blood transfusion in burn patients: Triggers of transfusion in a referral burn center in Iran.

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine·2017

Related Experiment Video

Updated: Jun 19, 2026

Tick Artificial Membrane Feeding for Ixodes scapularis
08:53

Tick Artificial Membrane Feeding for Ixodes scapularis

Published on: November 30, 2022

Spider bite (latrodectism) in Mashhad, Iran.

R Afshari1, M Khadem-Rezaiyan, M Balali-Mood

  • 1Medical Toxicology Research Centre, Imam Reza (p) University Hospital, Mashhad University of Medical Sciences, Mashhad, I.R. Iran. AfshariR@mums.ac.ir

Human & Experimental Toxicology
|October 9, 2009
PubMed
Summary

Latrodectus tredecimguttatus spider bites are common in Iran, causing pain and other symptoms. Electrocardiogram (ECG) monitoring is recommended due to potential cardiac toxicity, especially when antivenom is unavailable.

More Related Videos

A Model for Experimental Exposure of Humans to Larval Ixodes scapularis Ticks
04:47

A Model for Experimental Exposure of Humans to Larval Ixodes scapularis Ticks

Published on: December 1, 2023

Related Experiment Videos

Last Updated: Jun 19, 2026

Tick Artificial Membrane Feeding for Ixodes scapularis
08:53

Tick Artificial Membrane Feeding for Ixodes scapularis

Published on: November 30, 2022

A Model for Experimental Exposure of Humans to Larval Ixodes scapularis Ticks
04:47

A Model for Experimental Exposure of Humans to Larval Ixodes scapularis Ticks

Published on: December 1, 2023

Area of Science:

  • Toxicology
  • Clinical Medicine
  • Epidemiology

Background:

  • Latrodectus tredecimguttatus spider bites are a frequent occurrence in Northeast Iran.
  • These envenomations can lead to significant morbidity and, rarely, mortality.

Purpose of the Study:

  • To investigate the clinical manifestations, electrocardiographic changes, and laboratory findings in patients bitten by Latrodectus tredecimguttatus.
  • To assess the outcomes of supportive and symptomatic treatment in the absence of specific antivenom.

Main Methods:

  • Prospective study of consecutive patients admitted with suspected spider bites over a one-year period.
  • Clinical assessment, electrocardiography (ECG), and laboratory tests were performed on all patients.

Main Results:

  • Spider bites represented 0.5% of all poisonings, with pain being the most common symptom (90%).
  • Electrocardiographic abnormalities, specifically ST segment depression, were observed in 25% of cases.
  • All patients recovered with supportive care, averaging 1.9 days of hospitalization.

Conclusions:

  • Latrodectus tredecimguttatus envenomation in Mashhad presents with distinct clinical and cardiac findings.
  • ECG monitoring is crucial for managing these bites, particularly in regions lacking specific antivenom.