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Cardiogenic shock with hypereosinophilic syndrome

Vinitha Prasad1, L Rajam, Ashwin Borade

  • 1Department of Pediatrics, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India. vinithaprasad@aims.amrita.edu

Indian Pediatrics
|October 9, 2009
PubMed

Insights

A child with hypereosinophilic syndrome experienced cardiogenic shock, skin, and joint issues. Steroid therapy led to remission, with low-dose prednisolone maintaining the patient's condition.

Area of Science:

  • Pediatrics
  • Hematology
  • Cardiology

Background:

  • Hypereosinophilic syndrome (HES) is a rare disorder characterized by persistent high eosinophil counts.
  • HES can affect multiple organ systems, including the heart, skin, and joints.
  • Cardiogenic shock is a life-threatening condition caused by severe heart dysfunction.

Observation:

  • A pediatric patient presented with symptoms of cardiogenic shock.
  • The patient also exhibited significant skin and joint involvement.
  • Initial eosinophil counts were markedly elevated, indicative of hypereosinophilia.

Findings:

  • Steroid therapy resulted in clinical improvement and normalization of eosinophil counts.
  • Discontinuation of steroids led to relapse of skin lesions and hypereosinophilia.
  • Low-dose prednisolone effectively maintained the patient in remission.

Implications:

  • Early diagnosis and prompt treatment are crucial for managing pediatric hypereosinophilic syndrome.
  • Corticosteroids are effective in inducing and maintaining remission in HES.
  • This case highlights the potential cardiac, dermatologic, and rheumatologic manifestations of HES in children.

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