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Conduction block of peripheral nerve using high-frequency alternating currents delivered through an intrafascicular
D Michael Ackermann1, Emily L Foldes, Niloy Bhadra
1Case Western Reserve University, Cleveland, Ohio, USA.
Muscle & Nerve
|October 9, 2009
Abstract
None:
Many diseases are characterized by undesired or pathological neural activity. The local delivery of high-frequency currents has been shown to be an effective method for blocking neural conduction in peripheral nerves and may provide a therapy for these conditions. To date, all studies of high-frequency conduction block have utilized extraneural (cuff) electrodes to achieve conduction block. In this study we show that high-frequency conduction block is feasible using intrafascicular electrodes.

