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Murine Fetal Echocardiography
Published on: February 15, 2013
Evaluation of regional left ventricular longitudinal function in 151 normal fetuses using velocity vector imaging
Qing-Hai Peng1, Qi-Chang Zhou, Shi Zeng
1Department of Ultrasonography, The Second Xiangya Hospital of Central South University, Changsha, 410011, PR China.
Prenatal Diagnosis
|October 9, 2009
Summary
Velocity Vector Imaging (VVI) provides a novel, noninvasive method to assess fetal heart function. This study establishes normative data for fetal myocardial velocity, strain, and strain rate in Chinese populations.
Area of Science:
- Cardiology
- Fetal Medicine
- Medical Imaging
Background:
- Assessing fetal cardiac function is crucial for prenatal care.
- Noninvasive methods for evaluating regional myocardial performance are needed.
Purpose of the Study:
- To evaluate the clinical utility of Velocity Vector Imaging (VVI) for assessing normal fetal regional myocardial performance.
- To establish normative data for Chinese fetuses using VVI.
Main Methods:
- 151 healthy Chinese fetuses were grouped by gestational age.
- Digital dynamic four-chamber views were analyzed offline.
- Regional tissue velocity, strain, and strain rate of interventricular septum and left lateral wall were measured.
Main Results:
- Normative systolic and diastolic values for fetal myocardial velocity, strain, and strain rate were established.
- Tissue velocity decreased from base to apex and varied with gestational age.
- Strain and strain rate remained stable across segments and gestation.
Conclusions:
- VVI is a valuable noninvasive tool for quantitative assessment of fetal regional systolic and diastolic function.
- Fetal myocardial velocity, strain, and strain rate measurements are easily and reproducibly obtained.
- This technique aids in evaluating fetal cardiac function.

