Related Experiment Video

Updated: Jun 19, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
12:49

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model

Published on: August 17, 2022

Donor factors that affect the number of organs transplanted per donor

Leslie Olson1, Lynn Cravero

  • 1LifeCenter Northwest, Bellevue, WA 98004, USA. leso@lcnw.org

Progress in Transplantation (Aliso Viejo, Calif.)
|October 10, 2009
PubMed

Insights

Donor demographics and medical history significantly impact organ transplantation numbers. Identifying these factors can help optimize organ recovery and transplantation rates.

Area of Science:

  • Transplantation Medicine
  • Public Health
  • Biostatistics

Background:

  • Organ donor characteristics significantly influence the number of organs transplanted per donor.
  • Organ procurement organizations aim for an average of 4.30 organs transplanted per standard criteria donor.

Purpose of the Study:

  • To investigate how donor demographics and medical/social history affect the number of organs transplanted per donor.
  • To identify specific factors that correlate with reduced organ yield per donor.

Main Methods:

  • Retrospective review of medical and social histories for 772 deceased organ donors.
  • Assessment of demographic factors (age, sex), diseases (heart disease, diabetes, hypertension), and social factors (high-risk behavior, alcohol abuse).
  • Statistical analysis using MarketSight software to determine factor influence.

Main Results:

  • A total of 2409 organs were transplanted from 772 donors between 2003-2007, averaging 3.12 organs per donor.
  • Donor age and sex were associated with a lower number of organs transplanted per donor.
  • Each additional medical or social risk factor in a donor's history significantly decreased the number of organs transplanted.

Conclusions:

  • Donor demographic and medical/social history factors significantly reduce the number of organs transplanted per donor.
  • Development of a predictive algorithm incorporating demographic and nested medical/social history factors is proposed to estimate organ yield.
Abstract

More Related Videos

Ex Situ Normothermic Machine Perfusion of Donor Livers12:13

Ex Situ Normothermic Machine Perfusion of Donor Livers

Published on: May 26, 2015

Study of Experimental Organ Donation Models for Lung Transplantation08:56

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...