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Related Concept Videos

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Antiasthma Drugs: Leukotriene Modifiers01:19

Antiasthma Drugs: Leukotriene Modifiers

Leukotriene modifiers, or cysteinyl leukotriene receptor antagonists, are medications used to manage chronic asthma. These agents target specific inflammatory mediators produced during arachidonic acid metabolism, an essential process in generating inflammation in the body.
Leukotriene modifiers work through two distinct mechanisms:
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

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Updated: Jun 19, 2026

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
05:56

A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

Published on: May 12, 2023

Immunomodulators in asthma therapy.

Vesselin V Dimov, Jeffrey R Stokes, Thomas B Casale

    Current Allergy and Asthma Reports
    |October 10, 2009
    PubMed
    Summary
    This summary is machine-generated.

    Novel immunomodulators show promise for allergy and immunology treatments, including asthma. This review details their efficacy and safety from clinical trials.

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    Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
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    Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

    Published on: April 16, 2019

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    Last Updated: Jun 19, 2026

    A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion
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    A Traditional Chinese Medicine Characteristic Therapy for Bronchial Asthma: Moxibustion

    Published on: May 12, 2023

    Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
    10:39

    Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy

    Published on: April 16, 2019

    Area of Science:

    • Allergy and Immunology
    • Immunotherapy

    Background:

    • Recent advancements in allergy and immunology have introduced novel therapeutic strategies.
    • Several new agents are currently undergoing clinical trials for various immune-related conditions.

    Purpose of the Study:

    • To review human clinical trial data on immunomodulators for allergy and immunology.
    • To discuss the rationale, efficacy, and adverse events of these novel therapeutic approaches.

    Main Methods:

    • Summarization of data from human clinical trials involving immunomodulators.
    • Analysis of therapeutic approaches including Toll-like receptor agonists, cytokine blockers, and transcription factor modulators.

    Main Results:

    • Omalizumab (anti-IgE monoclonal antibody) is effective for allergic asthma, though patient selection criteria need refinement.
    • Various immunomodulators targeting specific pathways are under evaluation for asthma treatment.

    Conclusions:

    • Emerging immunomodulatory agents offer new therapeutic avenues in allergy and immunology.
    • Further research is needed to optimize patient selection and understand the full potential of these treatments.