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Ferromagnetic Bare Metal Stent for Endothelial Cell Capture and Retention
Published on: September 18, 2015
Developments in metallic biodegradable stents
H Hermawan1, D Dubé, D Mantovani
1Laboratory for Biomaterials and Bioengineering, Department of Mining, Metallurgical and Materials Engineering & University Hospital Research Center, Laval University, Pav Adrien-Pouliot, 1745-E, Laval University, 1065 Ave de la Médecine, Québec City, QC, Canada.
Acta Biomaterialia
|October 10, 2009
Summary
Metallic biodegradable stents offer temporary support for narrowed arteries, gradually disappearing as the vessel heals. Recent advancements have progressed these innovative medical devices into human clinical trials.
Area of Science:
- Biomaterials Science
- Cardiovascular Engineering
- Medical Device Development
Background:
- Growing research interest in metallic degradable biomaterials over the past decade.
- Increased publications in scientific journals and patent databases highlight this trend.
- Temporary biomedical implants, like coronary stents, are key applications.
Purpose of the Study:
- To review the development of biodegradable stents, focusing on metallic materials.
- To trace advancements from initial design concepts to validation testing.
- To analyze trends based on patent and journal publications.
Main Methods:
- Literature review of scientific journals.
- Analysis of patent databases.
- Focus on metallic biodegradable stents and their evolution.
Main Results:
- Significant increase in research and patents related to metallic degradable biomaterials.
- Biodegradable metallic stents are progressing towards clinical application.
- Early 2000s marked the introduction of biodegradable metallic stents, now in human trials.
Conclusions:
- Biodegradable metallic stents represent a promising advancement in temporary vascular implants.
- Continued research and development are driving the clinical translation of these devices.
- The review highlights the trajectory from concept to validation testing in this field.
