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Updated: Jun 19, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
Unilateral hydronephrosis due to ureteropelvic junction obstruction in children: long term follow-up
N Zampieri1, C Zamboni, A Ottolenghi
1Department of Surgical Sciences, Pediatric Surgical Unit, G.B. Rossi Polyclinic, University of Verona, Verona, Italy. dr.zampieri@libero.it
Aim:
Hydronephrosis is one of the most common urological disease detected on prenatal ultrasound; The aim of this study was evaluate the role of long-term follow-up in patients with unilateral hydronephrosis.
Methods:
On January 2009, the medical charts of patients observed at the Department and Institution for unilateral hydronephrosis were reviewed, for a long-term follow-up evaluation (10 years). All diagnosis were done prenatally. Long term follow-up is described.
Results:
One hundred and seventy-four 174 patients were observed. At diagnosis grading of hydronephrosis was: 3% grade 0, 25% grade I, 41% grade II, 31% grade IV. At the end of the study, 94 patients underwent surgery, while 80 were managed conservatively.
Conclusions:
Grade of hydronephrosis and renal function still remain the most important variables to decide the surgical management. Long-term follow-up shows that over the years many patients need surgery.
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