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Updated: Jun 19, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Adherence to acute migraine medication: what does it mean, why does it matter?
Bozena J Katić1, Steven J Krause, Stewart J Tepper
1Merck & Co., Inc, Global Outcomes Research, Whitehouse Station, NJ, USA.
Headache
|October 13, 2009
Summary
Migraine patients often stop or delay effective treatments like triptans. Understanding medication persistence requires considering patient beliefs and physician relationships, not just drug factors.
Area of Science:
- Neurology
- Pharmacology
- Health Services Research
Background:
- Migraine management relies on proper medication use, but patients frequently alter or discontinue effective therapies.
- Medication persistence in chronic episodic disorders like migraine remains poorly understood.
Purpose of the Study:
- To review and synthesize existing research on acute medication use and persistence in migraine management.
- To identify factors influencing sustained use of acute migraine medications.
Main Methods:
- Critical review of studies utilizing pharmacy claims, clinical records, surveys, and patient-reported data.
- Exploration of acute medication use patterns in migraine headache treatment.
Main Results:
- Medication efficacy, cost, tolerability, and side effects influence adherence.
- Low perceived disease importance and internal patient decision-making significantly impact sustained acute medication use.
- Physician-patient relationship factors also play a role in medication persistence.
Conclusions:
- A model integrating perceived migraine severity, medication safety beliefs, and physician-patient relationship factors can identify patients at risk for adherence issues.
- Improving medication persistence requires addressing both patient-centric and relationship-based factors.
- Further research is needed to refine predictive models for migraine medication adherence.
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