Related Experiment Video
Updated: Jun 19, 2026
05:19
A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Repeat dynamic sentinel node biopsy in locally recurrent penile carcinoma
Niels M Graafland1, Joost A P Leijte, Renato A Valdés Olmos
1Department of Urology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
BJU International
|October 13, 2009
Summary
Repeat dynamic sentinel node biopsy (SNB) is feasible for recurrent penile cancer in node-negative patients. This procedure can identify metastatic nodes even after prior surgery, aiding in treatment decisions for penile carcinoma.
Area of Science:
- Oncology
- Surgical Oncology
- Urologic Oncology
Background:
- Penile carcinoma recurrence presents challenges in clinical management.
- Sentinel node biopsy (SNB) is a standard staging procedure.
- Repeat SNB is considered for recurrent disease in node-negative patients.
Purpose of the Study:
- To evaluate the feasibility and accuracy of repeat dynamic sentinel node biopsy (SNB) in patients with locally recurrent penile carcinoma.
- To assess the role of repeat SNB in clinically node-negative patients previously treated with penile surgery and SNB.
Main Methods:
- A prospective database of dynamic sentinel node biopsy (SNB) was utilized.
- 12 patients with recurrent penile carcinoma underwent repeat SNB.
- Preoperative lymphoscintigraphy and blue-dye injection were employed, similar to primary SNB.
Main Results:
- Sentinel nodes were visualized in 19 of 24 undissected groins (79% identification rate).
- Positive sentinel nodes were found in 3 patients, with additional metastases in one case.
- One groin recurrence occurred 14 months post-repeat SNB in a patient with a tumor-negative sentinel node.
Conclusions:
- Repeat dynamic SNB is a feasible technique for clinically node-negative patients with recurrent penile carcinoma.
- The procedure can help identify nodal metastases in previously operated groins.
- Repeat SNB may guide further management in select cases of penile cancer recurrence.
