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Related Experiment Video

Updated: Jun 19, 2026

Murine Isolated Heart Model of Myocardial Stunning Associated with Cardioplegic Arrest

Murine Isolated Heart Model of Myocardial Stunning Associated with Cardioplegic Arrest

Published on: August 6, 2015

Neurogenic stunned myocardium.

Hoang Nguyen¹, Jonathan G Zaroff

¹Cardiology Department, Kaiser San Francisco Medical Center, San Francisco, CA 94115, USA.

Current Neurology and Neuroscience Reports

|October 13, 2009

Summary

Neurogenic stunned myocardium is heart injury after brain injury due to autonomic imbalance. These cardiac issues are reversible, with treatment focused on the brain injury itself.

Area of Science:

Cardiology
Neurology
Autonomic Nervous System

Background:

Acute brain injury can trigger cardiac abnormalities.
Autonomic nervous system imbalance plays a key role in neurogenic stunned myocardium.
This condition involves myocardial injury and dysfunction following brain insults.

Purpose of the Study:

To define neurogenic stunned myocardium.
To outline the spectrum of cardiac abnormalities associated with this condition.
To provide guidance on management strategies.

Main Methods:

Observational analysis of cardiac manifestations post-brain injury.
Assessment of autonomic nervous system function.
Monitoring of cardiac parameters and biomarkers.

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Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography

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Last Updated: Jun 19, 2026

Murine Isolated Heart Model of Myocardial Stunning Associated with Cardioplegic Arrest

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Published on: August 6, 2015

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model

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Published on: September 3, 2020

Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography

Confirmation of Myocardial Ischemia and Reperfusion Injury in Mice Using Surface Pad Electrocardiography

Published on: November 24, 2016

Main Results:

Neurogenic stunned myocardium presents with ECG changes, arrhythmias, and myocardial necrosis.
Left ventricular systolic and diastolic dysfunction are observed.
Elevated B-type natriuretic peptide levels indicate cardiac strain.

Conclusions:

Neurogenic stunned myocardium is a reversible condition linked to acute brain injury.
Management requires careful cardiac monitoring.
Therapeutic focus should be on addressing the primary neurological condition for optimal recovery.