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Updated: Jun 19, 2026
05:28
Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors
Published on: May 12, 2022
Plasmodium malariae in Bangladesh.
W Rahman1, K Chotivanich, K Silamut
1Chittagong Medical College Hospital, Chittagong, Bangladesh.
Transactions of the Royal Society of Tropical Medicine and Hygiene
|October 13, 2009
Summary
Severe malaria caused by Plasmodium malariae is rare. This case highlights rosetting as a potential factor in severe Plasmodium malariae infections, with successful treatment using quinine.
Area of Science:
- Malariology
- Infectious Diseases
- Hematology
Background:
- Severe malaria is typically associated with Plasmodium falciparum.
- Plasmodium malariae is known to cause chronic infections, but severe presentations are exceptionally uncommon.
Observation:
- A case of severe malaria in a 32-year-old Bangladeshi male is presented.
- The patient had a mono-infection with Plasmodium malariae.
- Erythrocyte rosetting, a phenomenon previously linked to Plasmodium falciparum virulence, was observed.
Findings:
- This report documents an extremely rare case of severe disease caused by Plasmodium malariae.
- The presence of rosetting in this Plasmodium malariae infection suggests a potential role in disease severity.
Implications:
- This case expands the understanding of Plasmodium malariae pathogenicity.
- It underscores the importance of considering less common Plasmodium species in severe malaria diagnoses.
- Effective treatment with intravenous quinine was achieved, indicating standard antimalarial therapies remain viable.
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