Fast free-form deformation using graphics processing units
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Updated: Jun 19, 2026

Free-form Light Actuators — Fabrication and Control of Actuation in Microscopic Scale
Published on: May 25, 2016
Marc Modat1, Gerard R Ridgway, Zeike A Taylor
1Centre for Medical Image Computing, Department of Medical Physics and Bioengineering, University College London, London, UK. m.modat@ucl.ac.uk
Abstract:
A large number of algorithms have been developed to perform non-rigid registration and it is a tool commonly used in medical image analysis. The free-form deformation algorithm is a well-established technique, but is extremely time consuming. In this paper we present a parallel-friendly formulation of the algorithm suitable for graphics processing unit execution. Using our approach we perform registration of T1-weighted MR images in less than 1 min and show the same level of accuracy as a classical serial implementation when performing segmentation propagation. This technology could be of significant utility in time-critical applications such as image-guided interventions, or in the processing of large data sets.
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