Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mechanistic Models: Compartment Models in Individual and Population Analysis

Mechanistic Models: Compartment Models in Individual and Population Analysis

Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least squares (OLS)...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

ACMT Practice Statement: Duration of Intravenous Acetylcysteine Therapy Following Acetaminophen Overdose (2026 Update).

Journal of medical toxicology : official journal of the American College of Medical Toxicology·2026

Same author

Interpreting Fentanyl and Norfentanyl Concentrations among Patients Seen in the Emergency Department after a Nonfatal Opioid Overdose: A Multicenter Study.

Journal of medical toxicology : official journal of the American College of Medical Toxicology·2026

Same author

Severe and Refractory Precipitated Opioid Withdrawal Induced by Samidorphan.

The American journal of psychiatry·2026

Same author

Effect of various mediums on water bead expansion in acidic and neutral solutions.

Clinical toxicology (Philadelphia, Pa.)·2025

Same author

Clinical Features of Paralytic Shellfish Poisoning: a Case Series from the 2024 Oregon Outbreak.

Journal of medical toxicology : official journal of the American College of Medical Toxicology·2025

Same author

An evaluation of the current case reporting of extracorporeal membrane oxygenation use in poisoned patients and recommendations for further improvement.

Clinical toxicology (Philadelphia, Pa.)·2025

Search research articles

Related Experiment Video

Updated: Jun 19, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

Methamphetamine body stuffers: an observational case series.

Patrick L West¹, Nathanael J McKeown, Robert G Hendrickson

¹Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA. westp@ohsu.edu

Annals of Emergency Medicine

|October 13, 2009

Summary

Methamphetamine body stuffers, individuals who conceal drugs internally, frequently ingest large doses, leading to severe outcomes in 29% of cases. Early signs of severe toxicity include elevated pulse rate and temperature.

More Related Videos

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

Neurotoxicity Assessment in Adult Danio rerio using a Battery of Behavioral Tests in a Single Tank

Neurotoxicity Assessment in Adult Danio rerio using a Battery of Behavioral Tests in a Single Tank

Published on: November 3, 2023

Related Experiment Videos

Last Updated: Jun 19, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

Neurotoxicity Assessment in Adult Danio rerio using a Battery of Behavioral Tests in a Single Tank

Neurotoxicity Assessment in Adult Danio rerio using a Battery of Behavioral Tests in a Single Tank

Published on: November 3, 2023

Area of Science:

Toxicology
Emergency Medicine
Pharmacology

Background:

Body stuffing is a method of concealing drugs internally to avoid detection.
Methamphetamine body stuffers present unique challenges in emergency medicine due to potential for acute toxicity.

Purpose of the Study:

To describe the demographics, characteristics, treatment, and clinical course of methamphetamine body stuffers.
To identify clinical predictors of severe outcomes in methamphetamine body stuffers.

Main Methods:

A 6.5-year descriptive, nonconcurrent observational case series.
Involved consultation with the Oregon Poison Center for patients with methamphetamine exposure.
Supplemented poison center charts with hospital charts for 95% of patients.

Main Results:

Fifty-five cases of methamphetamine body stuffers were identified.
The majority were young adult males who ingested methamphetamine orally, often unpackaged.
Twenty-nine percent of patients experienced severe outcomes, including end-organ toxicity and agitation requiring intubation; one death was reported.

Conclusions:

Methamphetamine body stuffers exhibit distinct ingestion patterns and a higher rate of severe outcomes compared to other stimulant body stuffers.
Elevated presenting pulse rate (>120 bpm) or temperature (>38.0°C) are key indicators of potential end-organ damage.