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Updated: Jun 19, 2026
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Chinese Herbal Retention Enema for the Treatment of Ulcerative Colitis
Published on: May 16, 2025
Hypoglycemia-like symptoms after restorative proctocolectomy for UC: a preliminary study
Makoto Tanaka1, Yoshie Murakami, Tsuneo Fukushima
1Department of Adult Nursing/Palliative Care Nursing, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. hmakoto-tky@umin.ac.jp
Summary
Hypoglycemia-like symptoms are common after proctocolectomy for ulcerative colitis. These symptoms, including cold sweats and trembling, affect a significant portion of patients post-surgery.
Area of Science:
- Gastroenterology
- Surgical Outcomes
- Endocrinology
Background:
- Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
- Proctocolectomy is a surgical option for UC, sometimes leading to post-operative symptoms.
- Hypoglycemia-like symptoms have been anecdotally reported after this procedure.
Purpose of the Study:
- To investigate the prevalence of hypoglycemia-like symptoms following proctocolectomy for UC.
- To assess patient recognition and triggers of these symptoms.
- To compare symptom occurrence between staged and one-staged proctocolectomy procedures.
Main Methods:
- A cohort of 83 patients who underwent restorative proctocolectomy for UC were surveyed.
- Questionnaires assessed 18 hypoglycemia-like symptoms, symptom recognition, and relief after eating.
- Data were collected at the temporary ileostomy stage and after stoma closure.
Main Results:
- 14% of patients reported specific hypoglycemia-like symptoms (cold sweats, trembling, extreme sweets desire) with a temporary ileostomy.
- Post-operation, 20% (staged) and 27.3% (one-staged) experienced these symptoms.
- No significant difference in symptom prevalence was observed between the surgical approaches.
Conclusions:
- Hypoglycemia-like symptoms are a considerable concern for patients after proctocolectomy for ulcerative colitis.
- The findings highlight the need for awareness and potential management strategies for these post-surgical symptoms.
- Further research may elucidate the mechanisms and optimal interventions for these symptoms.
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