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Updated: Jun 19, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Optimized multidetector computed tomographic protocol for the diagnosis of active obscure gastrointestinal bleeding:
Peter Heiss1, Niels Zorger, Okka W Hamer
1Department of Radiology, University of Regensburg, 93042 Regensburg, Germany. heiss.peter@web.de
Optimized multidetector computed tomography (MDCT) effectively diagnoses active obscure gastrointestinal bleeding (OGIB). This feasibility study shows MDCT is an excellent tool for identifying bleeding sites and sources in patients with OGIB.
Area of Science:
- Radiology
- Gastroenterology
Background:
- Obscure gastrointestinal bleeding (OGIB) presents diagnostic challenges.
- Timely diagnosis is crucial for effective patient management.
Purpose of the Study:
- To prospectively evaluate an optimized multidetector computed tomography (MDCT) protocol.
- To assess MDCT's diagnostic accuracy for active OGIB.
Main Methods:
- A prospective, unicenter feasibility study included patients with active OGIB.
- Oral and rectal water served as luminal contrast.
- Contrast-enhanced 16-row MDCT (arterial and venous phases) was performed.
- Mesenteric digital subtraction angiography (DSA) was the reference standard.
Main Results:
- MDCT identified the bleeding site and source in 5 out of 6 patients (83%).
- DSA was positive in only 1 out of 4 patients (25%).
- MDCT detected bleeding in 2 patients with negative DSA results.
Conclusions:
- Optimized MDCT is a highly effective diagnostic tool for active OGIB.
- MDCT demonstrates superior sensitivity compared to DSA in this feasibility study.
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