Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Toxic Reactions: Overview01:26

Toxic Reactions: Overview

When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Bioactivation and Tissue Toxicity01:25

Bioactivation and Tissue Toxicity

Bioactivation is a metabolic process that transforms less reactive substances into highly reactive metabolites, initiating tissue toxicity. This transformation can lead to various toxic effects, including carcinogenesis and teratogenesis. Reactive metabolites are classified into two main types: electrophiles and free radicals.Electrophiles are electron-deficient species and are produced primarily by the enzyme cytochrome P-450 during the metabolism of compounds containing carbon, nitrogen, or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toxicants, Exposome, and Hantavirus Disease: A One Health Perspective.

Viruses·2026
Same author

The burden of waste: Environmental justice, health risks, and socioeconomic disparities near waste management facilities.

Environmental research·2026
Same author

Monte Carlo-simulation risk assessment of oral exposure to bisphenols and phthalates via consumption of carbonated drinks from Iranian market.

Regulatory toxicology and pharmacology : RTP·2026
Same author

Aging in a highly polluted world: challenges and solutions to prevent Alzheimer's disease.

Archives of toxicology·2026
Same author

Polycyclic Aromatic Hydrocarbons Through the One Health Lens: Integrating Human, Animal, and Environmental Health Perspectives.

Toxics·2026
Same author

Postnatal particulate matter exposure alters developmental milestones and brain gene expression in apoE transgenic mice in a sex- and genotype-dependent manner.

Neurotoxicology·2026

Related Experiment Video

Updated: Jun 19, 2026

Flame Experiments at the Advanced Light Source: New Insights into Soot Formation Processes
10:04

Flame Experiments at the Advanced Light Source: New Insights into Soot Formation Processes

Published on: May 26, 2014

Toxic emissions from crematories: a review.

Montse Mari1, José L Domingo2

  • 1Laboratory of Toxicology and Environmental Health, School of Medicine, IISPV, "Rovira i Virgili" University, Sant Llorens 21, 43201 Reus, Catalonia, Spain; Environmental Engineering Laboratory, ETSEQ, "Rovira i Virgili" University, Av. Països Catalans 26, 43007 Tarragona, Catalonia, Spain.

Environment International
|October 14, 2009
PubMed
Summary
This summary is machine-generated.

Crematories emit lower levels of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) than other incinerators, but mercury emissions warrant attention. Further research on crematoria emissions and health risks is needed.

More Related Videos

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock
14:34

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock

Published on: May 6, 2010

Lab-Scale Model to Evaluate Odor and Gas Concentrations Emitted by Deep Bedded Pack Manure
06:52

Lab-Scale Model to Evaluate Odor and Gas Concentrations Emitted by Deep Bedded Pack Manure

Published on: July 19, 2018

Related Experiment Videos

Last Updated: Jun 19, 2026

Flame Experiments at the Advanced Light Source: New Insights into Soot Formation Processes
10:04

Flame Experiments at the Advanced Light Source: New Insights into Soot Formation Processes

Published on: May 26, 2014

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock
14:34

Biocontained Carcass Composting for Control of Infectious Disease Outbreak in Livestock

Published on: May 6, 2010

Lab-Scale Model to Evaluate Odor and Gas Concentrations Emitted by Deep Bedded Pack Manure
06:52

Lab-Scale Model to Evaluate Odor and Gas Concentrations Emitted by Deep Bedded Pack Manure

Published on: July 19, 2018

Area of Science:

  • Environmental Science
  • Toxicology
  • Public Health

Background:

  • Cremation rates are rising globally, increasing concerns about crematories as sources of environmental pollutants.
  • Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and mercury are key pollutants of concern from crematories.
  • Limited research exists on PCDD/F and mercury emissions from crematories and associated health risks compared to other incineration processes.

Purpose of the Study:

  • To review and synthesize existing scientific literature on PCDD/F and mercury emissions from crematories.
  • To assess the health risks associated with these emissions.
  • To identify knowledge gaps in the current research.

Main Methods:

  • Systematic literature review using PubMed, Scopus, and Scirus databases.
  • Analysis of emission data from crematories and other incineration sources.
  • Evaluation of reported health risk assessments.

Main Results:

  • Crematories emit significantly lower levels of PCDD/Fs compared to other incineration sources.
  • Mercury emissions from crematories, while not extensively studied, should not be underestimated.
  • There is a notable scarcity of comprehensive studies on the health impacts of crematoria emissions.

Conclusions:

  • While PCDD/F emissions from crematories are relatively low, mercury emissions require careful consideration and further investigation.
  • The limited data highlights the need for increased research into crematoria emissions and their potential public health implications.
  • Understanding these emissions is crucial for environmental protection and public health policy development.