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Behavior profile of children with nephrotic syndrome

Prathama Guha1, Arun De, Malay Ghosal

  • 1Department of Psychiatry, Calcutta Medical College, 88 College Street, Kolkata - 700 073, West Bengal, India.

Indian Journal of Psychiatry
|October 14, 2009
PubMed

Insights

Children with nephrotic syndrome exhibit significantly higher rates of behavioral abnormalities compared to healthy peers. Relapse frequency and lower socioeconomic status are linked to these disturbances, highlighting the need for integrated psychosocial care.

Area of Science:

  • Pediatric Nephrology
  • Developmental Psychology
  • Behavioral Science

Background:

  • Nephrotic syndrome in children has a high relapse rate.
  • Behavioral and psychological difficulties are reported in children with nephrotic syndrome and their families.
  • Psychosocial aspects of care are often overlooked in clinical practice.

Purpose of the Study:

  • To determine the prevalence of behavioral abnormalities in children with nephrotic syndrome in Eastern India.
  • To compare the prevalence of these abnormalities with a control group of healthy school children.
  • To investigate the links between sociodemographic, disease, and treatment factors and behavioral abnormalities in children with nephrotic syndrome.

Main Methods:

  • The Developmental Psychopathology Checklist (DPCL) was used to assess 50 children with nephrotic syndrome and 51 controls.
  • Statistical analysis explored associations between sociodemographic, disease, and treatment variables and behavioral profiles.
  • The study design involved a case-control comparison.

Main Results:

  • Children with nephrotic syndrome had a 68% prevalence of behavioral disturbances, significantly higher than the 21.6% in controls.
  • Common abnormalities included hyperkinesis, obsessive-compulsive disorder, conduct disorder, and emotional disorder.
  • Nephrotic syndrome relapse frequency and low socioeconomic status were significantly associated with behavioral disturbances, even after adjusting for other factors.

Conclusions:

  • Behavioral abnormalities are highly prevalent in children with nephrotic syndrome.
  • Relapse frequency and socioeconomic status are key factors associated with these behavioral issues.
  • Integrated psychosocial support is crucial for managing children with nephrotic syndrome.
Abstract

Keywords:
Behavior disturbancenephrotic syndromepsychiatric profile

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