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Related Concept Videos

Standing Waves01:17

Standing Waves

Sometimes waves do not seem to move; rather, they just vibrate in place. Unmoving waves can be seen on the surface of a glass of milk kept in a refrigerator, which is one example of standing waves. Vibrations from the refrigerator motor create waves on the milk that oscillate up and down but do not seem to move across the surface. These waves are formed or created by the superposition of two or more identical moving waves in opposite directions. The waves move through each other, with their...
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Scientists identified the plasma membrane in the 1890s and its principal chemical components (lipids and proteins) by 1915. The model for plasma membrane structure, proposed in 1935 by Hugh Davson and James Danielli, was the first model to be widely accepted in the scientific community. The model was based on the plasma membrane's "railroad track" appearance in early electron micrographs. Davson and Danielli theorized that the plasma membrane's structure resembled a sandwich with the analogy of...
Asymmetric Lipid Bilayer01:35

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Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
Partial Differential Equations01:21

Partial Differential Equations

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Standing Waves in a Cavity

A household microwave and lasers are examples of standing electromagnetic waves in a cavity. When two conducting metal plates are placed parallel at the nodal planes, it creates a cavity where standing waves are formed. The cavity between the two planes is analogous to a stretched string held at the points x = 0 and x = L. Here, the distance 'L' between the two planes must be an integer multiple of half of the wavelength. The wavelengths that satisfy this condition are given by:

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Related Experiment Video

Updated: Jun 19, 2026

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions
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Published on: May 27, 2021

Dynamic patterns in a supported lipid bilayer driven by standing surface acoustic waves.

Martin Hennig1, Jürgen Neumann, Achim Wixforth

  • 1Center for Nanoscience, CeNS, Ludwig-Maximilians-Universität, Fakultät für Physik, Geschwister Scholl Platz 1, D-80539 München, Germany.

Lab on a Chip
|October 14, 2009
PubMed
Summary

This study introduces a novel method using surface acoustic waves (SAWs) to create dynamic, spatially controlled patterns in supported lipid bilayers (SLBs). This technology allows for reversible lipid organization without compromising membrane integrity, opening new avenues for bio-interfaces.

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Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

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Area of Science:

  • Biophysics
  • Materials Science
  • Surface Chemistry

Background:

  • Supported lipid bilayers (SLBs) are crucial for studying membrane properties.
  • Current methods for SLB manipulation are limited in spatial and temporal control.

Purpose of the Study:

  • To develop a new technology for controlled, dynamic patterning of lipid membranes.
  • To investigate the use of surface acoustic waves (SAWs) for creating lateral lipid concentration gradients.

Main Methods:

  • Utilizing surface acoustic waves (SAWs) on a piezoelectric substrate to generate standing waves.
  • Inducing lateral modulation of lipid concentration within supported lipid bilayers (SLBs).
  • Assessing membrane integrity and fluidity through diffusion constant measurements.

Main Results:

  • Demonstrated reversible pattern formation in lipid membranes using SAWs.
  • Confirmed that the SAW-induced patterning does not compromise the integrity of the lipid bilayer.
  • Showcased the ability to modulate lipid concentration spatially and temporally.

Conclusions:

  • SAW-based technology offers unprecedented control over lipid membrane organization.
  • This method enables the design of switchable interfaces for dynamic control of membrane-bound molecules.
  • Potential applications include creating dynamic bioarrays and controlling biofilm formation.