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Cerebral Ischemic Coma Model Induced by Modified Four-Vessel Occlusion
03:37

Cerebral Ischemic Coma Model Induced by Modified Four-Vessel Occlusion

Published on: July 5, 2024

[Mechanism of eclamptic coma development]

Iu S Podol'skiĭ, D A Khismatulin, I Kh Khapiĭ

    Anesteziologiia I Reanimatologiia
    |October 15, 2009
    PubMed

    Analysis of the course of the disease in 28 puerperas with eclamptic coma has ascertained that it develops only in the presence of hypokinetic circulation as a result of lower circulating blood volume and cardiac index, which is followed by a cerebral circulation reduction to the critical values due to blood flow in the cortical structures. To maintain high blood flow in the subcortical structures is one of the leading causes of vasogenic edema of brain glia, followed by impaired liquorodynamics, which indices eclampsia. Low sustained cerebral circulation as a consequence of inadequate intensive care favors the extent of edema to the cerebral cortical structures after relieving eclampsia.

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