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Updated: Jun 19, 2026

Myosin-Specific Adaptations of In vitro Fluorescence Microscopy-Based Motility Assays
Published on: February 4, 2021
[Myosins in nucleus]
Magdalena Sobczak1, Łukasz Majewski, Maria Jolanta Redowicz
1Pracownia Molekularnych Podstaw Ruchów Komórkowych, Zakład Biochemii, Instytut Biologii Doświadczalnej im. M. Nenckiego PAN, Warszawa.
Abstract:
Myosins, actin-dependent molecular motors are expressed in almost all eukaryotic cells where are engaged in a panoply of cellular processes such as muscle contraction, cell migration and adhesion, intracellular trafficking, cytokinesis, endocytosis and secretion. In recent years a number of reports has been published revealing nuclear localization of myosins as well as actin and actin-binding proteins. Namely, nuclear form of myosin IC (NMI), myosin VI, myosin XVIB and myosin XVIIIB were found in nucleus. NMI and myosin VI seem to be involved in gene transcription and possibly intranuclear transport. In this paper, current knowledge on the role of myosin motors in nucleus has been presented.
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