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Estimating equilibrium constants for aggregation from the product distribution of a dynamic combinatorial library

Rosemary A R Hunt1, R Frederick Ludlow, Sijbren Otto

  • 1Centre for Systems Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.

Organic Letters
|October 15, 2009
PubMed
Summary

Researchers developed a new numerical method to estimate equilibrium constants for aggregate formation in complex chemical systems. This method analyzes product distribution in dynamic combinatorial libraries, aiding the study of self-recognizing molecules.

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