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Related Concept Videos

Plant Breeding and Biotechnology01:59

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Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
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Related Experiment Video

Updated: Jun 19, 2026

Optimizing the Use of a Liquid Handling Robot to Conduct a High Throughput Forward Chemical Genetics Screen of Arabidopsis thaliana
11:58

Optimizing the Use of a Liquid Handling Robot to Conduct a High Throughput Forward Chemical Genetics Screen of Arabidopsis thaliana

Published on: April 30, 2018

Plant chemical genetics.

Peter McCourt1, Darrell Desveaux

  • 1Department of Cell & Systems Biology, University of Toronto, 25 Willcocks St, Toronto, ON, Canada. peter.mccourt@utoronto.ca

The New Phytologist
|October 15, 2009
PubMed
Summary
This summary is machine-generated.

Chemical genetics uses small molecules to probe gene function, complementing traditional genetic methods. This approach is powerful for dissecting complex biological processes in plants.

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Peptide-derived Method to Transport Genes and Proteins Across Cellular and Organellar Barriers in Plants
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Related Experiment Videos

Last Updated: Jun 19, 2026

Optimizing the Use of a Liquid Handling Robot to Conduct a High Throughput Forward Chemical Genetics Screen of Arabidopsis thaliana
11:58

Optimizing the Use of a Liquid Handling Robot to Conduct a High Throughput Forward Chemical Genetics Screen of Arabidopsis thaliana

Published on: April 30, 2018

Peptide-derived Method to Transport Genes and Proteins Across Cellular and Organellar Barriers in Plants
08:48

Peptide-derived Method to Transport Genes and Proteins Across Cellular and Organellar Barriers in Plants

Published on: December 16, 2016

Area of Science:

  • Plant Biology
  • Genetics
  • Chemical Biology

Background:

  • The genomics revolution necessitates understanding individual gene functions in vivo.
  • Traditional genetics relies on systematic gene perturbation to study consequences.
  • Small-molecule libraries and chemical synthesis offer new tools for functional biology.

Purpose of the Study:

  • To summarize the application of chemical genetics in plant biology.
  • To highlight how chemical genetics complements traditional genetic analysis.
  • To demonstrate the power of combining chemical and genetic approaches for dissecting biological processes.

Main Methods:

  • Screening of small-molecule libraries to identify compounds that perturb biological processes.
  • Utilizing chemical synthesis for creating novel chemical probes.
  • Integrating chemical genetics with traditional genetic perturbation techniques.

Main Results:

  • Chemical genetics provides a powerful alternative and complement to traditional genetic methods.
  • Specific examples illustrate the successful application of chemical genetics in plant biology.
  • The combination of chemical and genetic approaches enhances the dissection of gene function.

Conclusions:

  • Chemical genetics is a valuable tool for understanding gene function in vivo.
  • Integrating chemical and genetic analyses offers a robust strategy for biological discovery.
  • This combined approach accelerates the elucidation of complex biological pathways in plants.